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1.
Clin Hemorheol Microcirc ; 86(1-2): 205-211, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-37638424

RESUMO

The growth of cyanobacteria can vary considerably depending on the ambient temperature. Since the optimal growth temperature for Arthrospira platensis (strain SAG21.99) is not yet known, this was investigated in the present study. The study revealed that a process temperature of 30 °C seems to be optimal for the Arthrospira strain SAG21.99 cultivation in terms of a maximum biomass productivity. This was also true for the phycocyanin content which was at 30 °C significantly higher than at 20 or 40 °C.


Assuntos
Spirulina , Temperatura
2.
Clin Hemorheol Microcirc ; 78(2): 151-161, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33554896

RESUMO

Within the last years a comprehensive number of scientific studies demonstrated beneficial effect of Arthropira platensis (AP) as dietary supplement due to a high content of proteins, minerals and vitamins. Positive effects like promoting the immune system, reducing inflammation and an anti-oxidant capacity are reported. In this study, the effect of an aqueous AP extract on primary human venous endothelial cells (HUVEC) was investigated. In addition, the effect of AP on HUVEC treated with a bacterial toxin (lipopolysaccharide, LPA), inducing an activation of HUVEC and cellular detachment, was analyzed. Depending on the concentration of AP extract a significantly accelerated formation of an endothelial cell monolayer was observed. Furthermore, the detachment of HUVEC after LPA addition was dramatically reduced by AP. In conclusion, the data are promising and indicatory for an application of Arthrospira platensis in the clinical field.


Assuntos
Endotélio Vascular/citologia , Endotélio Vascular/efeitos dos fármacos , Lipopolissacarídeos/efeitos adversos , Ficocianina/farmacologia , Probióticos/farmacologia , Spirulina/química , Endotélio Vascular/patologia , Humanos , Técnicas In Vitro , Estudos Prospectivos
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